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Inherent Interfacial Mechanical Gradients in 3D Hydrogels Influence Tumor Cell Behaviors
Cells sense and respond to the rigidity of their microenvironment by altering their morphology and migration behavior. To examine this response, hydrogels with a range of moduli or mechanical gradients have been developed. Here, we show that edge effects inherent in hydrogels supported on rigid subs...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338483/ https://www.ncbi.nlm.nih.gov/pubmed/22558241 http://dx.doi.org/10.1371/journal.pone.0035852 |