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Early Functional Deficit and Microglial Disturbances in a Mouse Model of Amyotrophic Lateral Sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by selective motoneurons degeneration. There is today no clear-cut pathogenesis sequence nor any treatment. However growing evidences are in favor of the involvement, besides neurons, of several partners su...

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Detalles Bibliográficos
Autores principales: Gerber, Yannick Nicolas, Sabourin, Jean-Charles, Rabano, Miriam, Vivanco, Maria d M, Perrin, Florence Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338492/
https://www.ncbi.nlm.nih.gov/pubmed/22558300
http://dx.doi.org/10.1371/journal.pone.0036000