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White Matter Differences between Healthy Young ApoE4 Carriers and Non-Carriers Identified with Tractography and Support Vector Machines

The apolipoprotein E4 (ApoE4) is an established risk factor for Alzheimer's disease (AD). Previous work has shown that this allele is associated with functional (fMRI) changes as well structural grey matter (GM) changes in healthy young, middle-aged and older subjects. Here, we assess the diffu...

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Detalles Bibliográficos
Autores principales: O'Dwyer, Laurence, Lamberton, Franck, Matura, Silke, Scheibe, Monika, Miller, Julia, Rujescu, Dan, Prvulovic, David, Hampel, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338494/
https://www.ncbi.nlm.nih.gov/pubmed/22558310
http://dx.doi.org/10.1371/journal.pone.0036024