Cytotoxicity of Superoxide Dismutase 1 in Cultured Cells Is Linked to Zn(2+) Chelation

Neurodegeneration in protein-misfolding disease is generally assigned to toxic function of small, soluble protein aggregates. Largely, these assignments are based on observations of cultured neural cells where the suspect protein material is titrated directly into the growth medium. In the present s...

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Detalles Bibliográficos
Autores principales: Johansson, Ann-Sofi, Vestling, Monika, Zetterström, Per, Lang, Lisa, Leinartaitė, Lina, Karlström, Mikael, Danielsson, Jens, Marklund, Stefan L., Oliveberg, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338499/
https://www.ncbi.nlm.nih.gov/pubmed/22558346
http://dx.doi.org/10.1371/journal.pone.0036104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338499/
https://www.ncbi.nlm.nih.gov/pubmed/22558346
http://dx.doi.org/10.1371/journal.pone.0036104

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