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Amniotic Epithelial Cells from the Human Placenta Potently Suppress a Mouse Model of Multiple Sclerosis

Human amniotic epithelial cells (hAEC) have stem cell-like features and immunomodulatory properties. Here we show that hAEC significantly suppressed splenocyte proliferation in vitro and potently attenuated a mouse model of multiple sclerosis (MS). Central nervous system (CNS) CD3(+) T cell and F4/8...

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Detalles Bibliográficos
Autores principales: Liu, Yu Han, Vaghjiani, Vijesh, Tee, Jing Yang, To, Kelly, Cui, Peng, Oh, Ding Yuan, Manuelpillai, Ursula, Toh, Ban-Hock, Chan, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338525/
https://www.ncbi.nlm.nih.gov/pubmed/22563398
http://dx.doi.org/10.1371/journal.pone.0035758