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TDP-43 Identified from a Genome Wide RNAi Screen for SOD1 Regulators

Amyotrophic Lateral Sclerosis (ALS) is a late-onset, progressive neurodegenerative disease affecting motor neurons in the brain stem and spinal cord leading to loss of voluntary muscular function and ultimately, death due to respiratory failure. A subset of ALS cases are familial and associated with...

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Detalles Bibliográficos
Autores principales: Somalinga, Balajee R., Day, Cameron E., Wei, Shuguang, Roth, Michael G., Thomas, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338536/
https://www.ncbi.nlm.nih.gov/pubmed/22563406
http://dx.doi.org/10.1371/journal.pone.0035818