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PAI-1-Dependent Endothelial Cell Death Determines Severity of Radiation-Induced Intestinal Injury
Normal tissue toxicity still remains a dose-limiting factor in clinical radiation therapy. Recently, plasminogen activator inhibitor type 1 (SERPINE1/PAI-1) was reported as an essential mediator of late radiation-induced intestinal injury. However, it is not clear whether PAI-1 plays a role in acute...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338537/ https://www.ncbi.nlm.nih.gov/pubmed/22563394 http://dx.doi.org/10.1371/journal.pone.0035740 |