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Immunological Responses and Actin Dynamics in Macrophages Are Controlled by N-Cofilin but Are Independent from ADF

Dynamic changes in the actin cytoskeleton are essential for immune cell function and a number of immune deficiencies have been linked to mutations, which disturb the actin cytoskeleton. In macrophages and dendritic cells, actin remodelling is critical for motility, phagocytosis and antigen presentat...

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Detalles Bibliográficos
Autores principales: Jönsson, Friederike, Gurniak, Christine B., Fleischer, Bernhard, Kirfel, Gregor, Witke, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338623/
https://www.ncbi.nlm.nih.gov/pubmed/22558315
http://dx.doi.org/10.1371/journal.pone.0036034