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Are Coiled-Coils of Dimeric Kinesins Unwound during Their Walking on Microtubule?
Dimeric kinesin motor proteins such as homodimeric kinesin-1, homodimeric Ncd and heterodimeric Kar3/Vik1are composed of two head domains which are connected together by a rod-shaped, coiled-coil stalk. Despite the extensive and intensive studies on structures, kinetics, dynamics and walking mechani...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338639/ https://www.ncbi.nlm.nih.gov/pubmed/22558333 http://dx.doi.org/10.1371/journal.pone.0036071 |