Aberrant Otx2 Expression Enhances Migration and Induces Ectopic Proliferation of Hindbrain Neuronal Progenitor Cells

Dysregulation of Otx2 is a hallmark of the pediatric brain tumor medulloblastoma, yet its functional significance in the establishment of these tumors is unknown. Here we have sought to determine the functional consequences of Otx2 overexpression in the mouse hindbrain to characterize its potential...

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Detalles Bibliográficos
Autores principales: Wortham, Matthew, Jin, Genglin, Sun, Julia Lailai, Bigner, Darell D., He, Yiping, Yan, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338642/
https://www.ncbi.nlm.nih.gov/pubmed/22558385
http://dx.doi.org/10.1371/journal.pone.0036211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338642/
https://www.ncbi.nlm.nih.gov/pubmed/22558385
http://dx.doi.org/10.1371/journal.pone.0036211

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