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Activation of Thiazide-Sensitive Co-Transport by Angiotensin II in the cyp1a1-Ren2 Hypertensive Rat

Transgenic rats with inducible expression of the mouse Ren2 gene were used to elucidate mechanisms leading to the development of hypertension and renal injury. Ren2 transgene activation was induced by administration of a naturally occurring aryl hydrocarbon, indole-3-carbinol (100 mg/kg/day by gastr...

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Detalles Bibliográficos
Autores principales: Ashek, Ali, Menzies, Robert I., Mullins, Linda J., Bellamy, Christopher O. C., Harmar, Anthony J., Kenyon, Christopher J., Flatman, Peter W., Mullins, John J., Bailey, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338649/
https://www.ncbi.nlm.nih.gov/pubmed/22558431
http://dx.doi.org/10.1371/journal.pone.0036311