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Role of Alpha-Synuclein Protein Levels in Mitochondrial Morphology and Cell Survival in Cell Lines

α-Synuclein is highly associated with some neurodegeneration and malignancies. Overexpressing wild-type or mutant α-synuclein promotes neuronal death by mitochondrial dysfunction, the underlying mechanisms of which remain poorly defined. It was recently reported that α-synuclein expression could dir...

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Detalles Bibliográficos
Autores principales: Zhu, Min, Li, Wenwei, Lu, Chuanzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338674/
https://www.ncbi.nlm.nih.gov/pubmed/22558453
http://dx.doi.org/10.1371/journal.pone.0036377