Cargando…

Transcriptome Sequencing Revealed Significant Alteration of Cortical Promoter Usage and Splicing in Schizophrenia

BACKGROUND: While hybridization based analysis of the cortical transcriptome has provided important insight into the neuropathology of schizophrenia, it represents a restricted view of disease-associated gene activity based on predetermined probes. By contrast, sequencing technology can provide un-b...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jing Qin, Wang, Xi, Beveridge, Natalie J., Tooney, Paul A., Scott, Rodney J., Carr, Vaughan J., Cairns, Murray J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338678/
https://www.ncbi.nlm.nih.gov/pubmed/22558445
http://dx.doi.org/10.1371/journal.pone.0036351