Cargando…

Sortilin Participates in Light-dependent Photoreceptor Degeneration in Vivo

Both proNGF and the neurotrophin receptor p75 (p75(NTR)) are known to regulate photoreceptor cell death caused by exposure of albino mice to intense illumination. ProNGF-induced apoptosis requires the participation of sortilin as a necessary p75(NTR) co-receptor, suggesting that sortilin may partici...

Descripción completa

Detalles Bibliográficos
Autores principales: Santos, Ana M., López-Sánchez, Noelia, Martín-Oliva, David, de la Villa, Pedro, Cuadros, Miguel A., Frade, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338683/
https://www.ncbi.nlm.nih.gov/pubmed/22558402
http://dx.doi.org/10.1371/journal.pone.0036243