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Clinical Utility of LC3 and p62 Immunohistochemistry in Diagnosis of Drug-Induced Autophagic Vacuolar Myopathies: A Case-Control Study

BACKGROUND: Some patients treated with chloroquine, hydroxychloroquine, or colchicine develop autophagic vacuolar myopathy, the diagnosis of which currently requires electron microscopy. The goal of the current study was to develop an immunohistochemical diagnostic marker for this pathologic entity....

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Detalles Bibliográficos
Autores principales: Lee, Han S., Daniels, Brianne H., Salas, Eduardo, Bollen, Andrew W., Debnath, Jayanta, Margeta, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338695/
https://www.ncbi.nlm.nih.gov/pubmed/22558391
http://dx.doi.org/10.1371/journal.pone.0036221