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Neoplastic Transformation of T Lymphocytes through Transgenic Expression of a Virus Host Modification Protein

Virus host evasion genes are ready-made tools for gene manipulation and therapy. In this work we have assessed the impact in vivo of the evasion gene A238L of the African Swine Fever Virus, a gene which inhibits transcription mediated by both NF-κB and NFAT. The A238L gene has been selectively expre...

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Detalles Bibliográficos
Autores principales: Almeida, Sílvia Cristina Paiva, de Oliveira, Vivian Leite, Ventura, Sónia, Bofill, Margarita, Parkhouse, Robert Michael Evans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338727/
https://www.ncbi.nlm.nih.gov/pubmed/22558084
http://dx.doi.org/10.1371/journal.pone.0034140