High-Throughput Sequencing of mGluR Signaling Pathway Genes Reveals Enrichment of Rare Variants in Autism

Identification of common molecular pathways affected by genetic variation in autism is important for understanding disease pathogenesis and devising effective therapies. Here, we test the hypothesis that rare genetic variation in the metabotropic glutamate-receptor (mGluR) signaling pathway contribu...

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Detalles Bibliográficos
Autores principales: Kelleher III, Raymond J., Geigenmüller, Ute, Hovhannisyan, Hayk, Trautman, Edwin, Pinard, Robert, Rathmell, Barbara, Carpenter, Randall, Margulies, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338748/
https://www.ncbi.nlm.nih.gov/pubmed/22558107
http://dx.doi.org/10.1371/journal.pone.0035003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338748/
https://www.ncbi.nlm.nih.gov/pubmed/22558107
http://dx.doi.org/10.1371/journal.pone.0035003

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