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IFN-λ3 Inhibits HIV Infection of Macrophages through the JAK-STAT Pathway

BACKGROUND: Interferon lambda 3 (IFN-λ3) is a newly identified cytokine with antiviral activity, and its single nucleotide polymorphisms are strongly associated with the treatment effectiveness and development of chronic hepatitis C virus infection. We thus examined the potential of IFN-λ3 to inhibi...

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Detalles Bibliográficos
Autores principales: Liu, Man-Qing, Zhou, Dun-Jin, Wang, Xu, Zhou, Wang, Ye, Li, Li, Jie-Liang, Wang, Yi-Zhong, Ho, Wen-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338759/
https://www.ncbi.nlm.nih.gov/pubmed/22558263
http://dx.doi.org/10.1371/journal.pone.0035902