Interaction of Pyrrolobenzodiazepine (PBD) Ligands with Parallel Intermolecular G-Quadruplex Complex Using Spectroscopy and ESI-MS

Studies on ligand interaction with quadruplex DNA, and their role in stabilizing the complex at concentration prevailing under physiological condition, has attained high interest. Electrospray ionization mass spectrometry (ESI-MS) and spectroscopic studies in solution were used to evaluate the inter...

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Detalles Bibliográficos
Autores principales: Raju, Gajjela, Srinivas, Ragampeta, Santhosh Reddy, Vangala, Idris, Mohammed M., Kamal, Ahmed, Nagesh, Narayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338766/
https://www.ncbi.nlm.nih.gov/pubmed/22558271
http://dx.doi.org/10.1371/journal.pone.0035920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338766/
https://www.ncbi.nlm.nih.gov/pubmed/22558271
http://dx.doi.org/10.1371/journal.pone.0035920

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