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ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

BACKGROUND: Neurons extend their dendrites and axons to build functional neural circuits, which are regulated by both positive and negative signals during development. Brain-derived neurotrophic factor (BDNF) is a positive regulator for neurite outgrowth and neuronal survival but the functions of it...

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Detalles Bibliográficos
Autores principales: Sun, Ying, Lim, Yoon, Li, Fang, Liu, Shen, Lu, Jian-Jun, Haberberger, Rainer, Zhong, Jin-Hua, Zhou, Xin-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338794/
https://www.ncbi.nlm.nih.gov/pubmed/22558255
http://dx.doi.org/10.1371/journal.pone.0035883