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ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA
BACKGROUND: Neurons extend their dendrites and axons to build functional neural circuits, which are regulated by both positive and negative signals during development. Brain-derived neurotrophic factor (BDNF) is a positive regulator for neurite outgrowth and neuronal survival but the functions of it...
Autores principales: | Sun, Ying, Lim, Yoon, Li, Fang, Liu, Shen, Lu, Jian-Jun, Haberberger, Rainer, Zhong, Jin-Hua, Zhou, Xin-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338794/ https://www.ncbi.nlm.nih.gov/pubmed/22558255 http://dx.doi.org/10.1371/journal.pone.0035883 |
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