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YAP1 Recruits c-Abl to Protect Angiomotin-Like 1 from Nedd4-Mediated Degradation

BACKGROUND: Tissue development and organ growth require constant remodeling of cell-cell contacts formed between epithelial cells. The Hippo signaling cascade curtails organ growth by excluding the transcriptional co-activator Yes Associated Protein 1 (YAP1) from the nucleus. Angiomotin family membe...

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Detalles Bibliográficos
Autores principales: Skouloudaki, Kassiani, Walz, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338797/
https://www.ncbi.nlm.nih.gov/pubmed/22558212
http://dx.doi.org/10.1371/journal.pone.0035735