Heart Failure-Inducible Gene Therapy Targeting Protein Phosphatase 1 Prevents Progressive Left Ventricular Remodeling

BACKGROUND: The targeting of Ca(2+) cycling has emerged as a potential therapy for the treatment of severe heart failure. These approaches include gene therapy directed at overexpressing sarcoplasmic reticulum (SR) Ca(2+) ATPase, or ablation of phospholamban (PLN) and associated protein phosphatase...

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Detalles Bibliográficos
Autores principales: Miyazaki, Yosuke, Ikeda, Yasuhiro, Shiraishi, Kozo, Fujimoto, Shizuka N., Aoyama, Hidekazu, Yoshimura, Koichi, Inui, Makoto, Hoshijima, Masahiko, Kasahara, Hideko, Aoki, Hiroki, Matsuzaki, Masunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338799/
https://www.ncbi.nlm.nih.gov/pubmed/22558250
http://dx.doi.org/10.1371/journal.pone.0035875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338799/
https://www.ncbi.nlm.nih.gov/pubmed/22558250
http://dx.doi.org/10.1371/journal.pone.0035875

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