Active Evasion of CTL Mediated Killing and Low Quality Responding CD8+ T Cells Contribute to Persistence of Brucellosis

Brucellosis is a common zoonotic disease that remains endemic in many parts of the world. Dissecting the host immune response during this disease provides insight as to why brucellosis is often difficult to resolve. We used a Brucella epitope specific in vivo killing assay to investigate the ability...

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Detalles Bibliográficos
Autores principales: Durward, Marina, Radhakrishnan, Girish, Harms, Jerome, Bareiss, Claire, Magnani, Diogo, Splitter, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338818/
https://www.ncbi.nlm.nih.gov/pubmed/22558103
http://dx.doi.org/10.1371/journal.pone.0034925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338818/
https://www.ncbi.nlm.nih.gov/pubmed/22558103
http://dx.doi.org/10.1371/journal.pone.0034925

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