Gα12 Activation in Podocytes Leads to Cumulative Changes in Glomerular Collagen Expression, Proteinuria and Glomerulosclerosis

Glomerulosclerosis is a common pathologic finding that often progresses to renal failure. The mechanisms of chronic kidney disease progression are not well-defined but may include activation of numerous vasoactive and inflammatory pathways. We hypothesized that podocytes are susceptible to filtered...

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Detalles Bibliográficos
Autores principales: Boucher, Ilene, Yu, Wanfeng, Beaudry, Sarah, Negoro, Hideyuki, Tran, Mei, Pollak, Martin, Henderson, Joel, Denker, Bradley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338890/
https://www.ncbi.nlm.nih.gov/pubmed/22249312
http://dx.doi.org/10.1038/labinvest.2011.198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338890/
https://www.ncbi.nlm.nih.gov/pubmed/22249312
http://dx.doi.org/10.1038/labinvest.2011.198

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