Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers

AIMS: To evaluate UFT and cyclophosphamide (CTX) based metronomic chemotherapy plus celecoxib (CXB) for the treatment of patients with heavily pre-treated advanced gastrointestinal malignancies. METHODS: Thirty-eight patients received 500 mg/mq(2) CTX i.v bolus on day 1 and, from day 2, 50 mg/day CT...

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Detalles Bibliográficos
Autores principales: Allegrini, Giacomo, Di Desidero, Teresa, Barletta, Maria Teresa, Fioravanti, Anna, Orlandi, Paola, Canu, Bastianina, Chericoni, Silvio, Loupakis, Fotios, Di Paolo, Antonello, Masi, Gianluca, Fontana, Andrea, Lucchesi, Sara, Arrighi, Giada, Giusiani, Mario, Ciarlo, Andrea, Brandi, Giovanni, Danesi, Romano, Kerbel, Robert S., Falcone, Alfredo, Bocci, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338912/
https://www.ncbi.nlm.nih.gov/pubmed/22382585
http://dx.doi.org/10.1007/s10456-012-9260-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338912/
https://www.ncbi.nlm.nih.gov/pubmed/22382585
http://dx.doi.org/10.1007/s10456-012-9260-6

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