Comparative modeling of CCRL1, a key protein in masked immune diseases and virtual screening for finding inhibitor of this protein

Human CCRL1 belongs to the family of silent chemokine receptors. This transmembrane protein plays a role in blunting function of chemokines through binding to them. This will attenuate immune responses. Interaction between CCRL1 and CCL21 determines this immune extinction. Thus inhibiting the action...

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Detalles Bibliográficos
Autores principales: Behjati, Mohaddeseh, Torktaz, Ibrahim, Mohammadpour, Mehrdad, Ahmadian, Gholamreza, Easton, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338979/
https://www.ncbi.nlm.nih.gov/pubmed/22553392
http://dx.doi.org/10.6026/97320630008336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338979/
https://www.ncbi.nlm.nih.gov/pubmed/22553392
http://dx.doi.org/10.6026/97320630008336

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