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Comparative modeling of CCRL1, a key protein in masked immune diseases and virtual screening for finding inhibitor of this protein
Human CCRL1 belongs to the family of silent chemokine receptors. This transmembrane protein plays a role in blunting function of chemokines through binding to them. This will attenuate immune responses. Interaction between CCRL1 and CCL21 determines this immune extinction. Thus inhibiting the action...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Biomedical Informatics
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338979/ https://www.ncbi.nlm.nih.gov/pubmed/22553392 http://dx.doi.org/10.6026/97320630008336 |