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Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats

We examine whether Phellodendron amurense (PA) and its major alkaloid compound, berberine (BER), improved memory defects caused by administering scopolamine in rats. Effects of PA and BER on the acetylcholinergic system and pro-inflammatory cytokines in the hippocampus were also investigated. Male r...

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Detalles Bibliográficos
Autores principales: Lee, Bombi, Sur, Bongjun, Shim, Insop, Lee, Hyejung, Hahm, Dae-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339292/
https://www.ncbi.nlm.nih.gov/pubmed/22563252
http://dx.doi.org/10.4196/kjpp.2012.16.2.79