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2D and 3D-QSAR study on 4-anilinoquinozaline derivatives as potent apoptosis inducer and efficacious anticancer agent

BACKGROUND: Apoptosis is known as programmed cell death that plays an important role in tumor biology. METHODS: In this study, apoptosis-inducing activity is predicted by using a QSAR modeling approach for a series of 4-anilinoquinozaline derivatives. 2D-QSAR model for the prediction of apoptosis-in...

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Detalles Bibliográficos
Autores principales: Vyas, Vivek Kumar, Ghate, Manjunath, Katariya, Hitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339342/
https://www.ncbi.nlm.nih.gov/pubmed/22373168
http://dx.doi.org/10.1186/2191-2858-1-13