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2D and 3D-QSAR study on 4-anilinoquinozaline derivatives as potent apoptosis inducer and efficacious anticancer agent
BACKGROUND: Apoptosis is known as programmed cell death that plays an important role in tumor biology. METHODS: In this study, apoptosis-inducing activity is predicted by using a QSAR modeling approach for a series of 4-anilinoquinozaline derivatives. 2D-QSAR model for the prediction of apoptosis-in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339342/ https://www.ncbi.nlm.nih.gov/pubmed/22373168 http://dx.doi.org/10.1186/2191-2858-1-13 |