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Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-(XL )expression

BACKGROUND: Thymoquinone (TQ), the major active component of the medicinal herb Nigella sativa Linn., has been described as a chemopreventive and chemotherapeutic compound. METHODS: In this study, we investigated the effect of TQ on survival, actin cytoskeletal reorganization, proliferation and sign...

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Detalles Bibliográficos
Autores principales: Badr, Gamal, Mohany, Mohamed, Abu-Tarboush, Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339355/
https://www.ncbi.nlm.nih.gov/pubmed/22177381
http://dx.doi.org/10.1186/1476-511X-10-236