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Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-(XL )expression
BACKGROUND: Thymoquinone (TQ), the major active component of the medicinal herb Nigella sativa Linn., has been described as a chemopreventive and chemotherapeutic compound. METHODS: In this study, we investigated the effect of TQ on survival, actin cytoskeletal reorganization, proliferation and sign...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339355/ https://www.ncbi.nlm.nih.gov/pubmed/22177381 http://dx.doi.org/10.1186/1476-511X-10-236 |