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Autocrine PDGF stimulation in malignancies

Platelet-derived growth factor (PDGF) isoforms are important mitogens for different types of mesenchymal cells, which have important functions during the embryonal development and in the adult during wound healing and tissue homeostasis. In tumors, PDGF isoforms are often over-expressed and contribu...

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Detalles Bibliográficos
Autor principal: Heldin, Carl-Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339540/
https://www.ncbi.nlm.nih.gov/pubmed/22512244
http://dx.doi.org/10.3109/03009734.2012.658119