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Glioblastoma—a moving target
The slow development of effective treatment of glioblastoma is contrasted by the rapidly advancing research on the molecular mechanisms underlying the disease. Amplification and overexpression of receptor tyrosine kinases, particularly EGFR and PDGFRA, are complemented by mutations in the PI3K, RB1,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Informa Healthcare
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339557/ https://www.ncbi.nlm.nih.gov/pubmed/22512247 http://dx.doi.org/10.3109/03009734.2012.676574 |