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Cataloguing functionally relevant polymorphisms in gene DNA ligase I: a computational approach

A computational approach for identifying functionally relevant SNPs in gene LIG1 has been proposed. LIG1 is a crucial gene which is involved in excision repair pathways and mutations in this gene may lead to increase sensitivity towards DNA damaging agents. A total of 792 SNPs were reported to be as...

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Detalles Bibliográficos
Autores principales: Singh, Abhishek A., Sivakumar, Dakshinamurthy, Somvanshi, Pallavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339591/
https://www.ncbi.nlm.nih.gov/pubmed/22558535
http://dx.doi.org/10.1007/s13205-011-0006-8