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Survey of human mitochondrial diseases using new genomic/proteomic tools

BACKGROUND: We have constructed Bayesian prior-based, amino-acid sequence profiles for the complete yeast mitochondrial proteome and used them to develop methods for identifying and characterizing the context of protein mutations that give rise to human mitochondrial diseases. (Bayesian priors are c...

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Detalles Bibliográficos
Autores principales: Plasterer, Thomas N, Smith, Temple F, Mohr, Scott C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC33397/
https://www.ncbi.nlm.nih.gov/pubmed/11423010