A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer

We described previously a screening protocol in Drosophila melanogaster that allows us to identify small molecules that increase the killing effect of ionizing radiation in vivo in a multicellular context. The ability of this screen to identify agents that enhance the effect of radiation in human ca...

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Detalles Bibliográficos
Autores principales: Gladstone, Mara, Frederick, Barbara, Zheng, Di, Edwards, Anthony, Yoon, Petros, Stickel, Stefanie, DeLaney, Tessie, Chan, Daniel C., Raben, David, Su, Tin Tin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339828/
https://www.ncbi.nlm.nih.gov/pubmed/22344740
http://dx.doi.org/10.1242/dmm.008722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339828/
https://www.ncbi.nlm.nih.gov/pubmed/22344740
http://dx.doi.org/10.1242/dmm.008722

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