An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice

Regions in the 8q24 gene desert contribute significantly to the risk of prostate cancer and other adult cancers. This region contains several DNA regions with enhancer activity in cultured cells. One such segment, histone acetylation peak 10 (AcP10), contains a risk single nucleotide polymorphism (S...

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Detalles Bibliográficos
Autores principales: Ting, Man-Chun, Liao, Chun-Peng, Yan, Chunli, Jia, Li, Groshen, Susan, Frenkel, Baruch, Roy-Burman, Pradip, Coetzee, Gerhard A., Maxson, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339830/
https://www.ncbi.nlm.nih.gov/pubmed/22279083
http://dx.doi.org/10.1242/dmm.008458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339830/
https://www.ncbi.nlm.nih.gov/pubmed/22279083
http://dx.doi.org/10.1242/dmm.008458

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