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Lipids in HIV's Envelope Help the Virus to Spread

An accessible sialyllactose moiety on viral membrane gangliosides is shown to be essential for HIV-1 uptake into mature dendritic cells, thereby promoting viral transfer and infection of bystander CD4+ T lymphocytes.

Detalles Bibliográficos
Autor principal: Sedwick, Caitlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339841/
https://www.ncbi.nlm.nih.gov/pubmed/22563298
http://dx.doi.org/10.1371/journal.pbio.1001316