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Structure and Mechanistic Insights into Novel Iron-mediated Moonlighting Functions of Human J-protein Cochaperone, Dph4

J-proteins are obligate cochaperones of Hsp70s and stimulate their ATPase activity via the J-domain. Although the functions of J-proteins have been well understood in the context of Hsp70s, their additional co-evolved “physiological functions” are still elusive. We report here the solution structure...

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Detalles Bibliográficos
Autores principales: Thakur, Anushikha, Chitoor, Balasubramanyam, Goswami, Arvind V., Pareek, Gautam, Atreya, Hanudatta S., D'Silva, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339945/
https://www.ncbi.nlm.nih.gov/pubmed/22367199
http://dx.doi.org/10.1074/jbc.M112.339655