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Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO(2) Sensing and Signaling
Carbon dioxide (CO(2)) is increasingly being appreciated as an intracellular signaling molecule that affects inflammatory and immune responses. Elevated arterial CO(2) (hypercapnia) is encountered in a range of clinical conditions, including chronic obstructive pulmonary disease, and as a consequenc...
Autores principales: | Oliver, Kathryn M., Lenihan, Colin R., Bruning, Ulrike, Cheong, Alex, Laffey, John G., McLoughlin, Paul, Taylor, Cormac T., Cummins, Eoin P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340129/ https://www.ncbi.nlm.nih.gov/pubmed/22396550 http://dx.doi.org/10.1074/jbc.M112.347971 |
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