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20-Hydroxyeicosatetraenoic Acid (20-HETE) Is a Novel Activator of Transient Receptor Potential Vanilloid 1 (TRPV1) Channel

TRPV1 is a member of the transient receptor potential ion channel family and is gated by capsaicin, the pungent component of chili pepper. It is expressed predominantly in small diameter peripheral nerve fibers and is activated by noxious temperatures >42 °C. 20-Hydroxyeicosatetraenoic acid (20-H...

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Detalles Bibliográficos
Autores principales: Wen, Hairuo, Östman, Johan, Bubb, Kristen J., Panayiotou, Catherine, Priestley, John V., Baker, Mark D., Ahluwalia, Amrita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340178/
https://www.ncbi.nlm.nih.gov/pubmed/22389490
http://dx.doi.org/10.1074/jbc.M111.334896