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Mechanisms of Unphosphorylated STAT3 Transcription Factor Binding to DNA

Phosphorylation of signal transducer and activator of transcription 3 (STAT3) on a single tyrosine residue in response to growth factors, cytokines, interferons, and oncogenes activates its dimerization, translocation to the nucleus, binding to the interferon γ (gamma)-activated sequence (GAS) DNA-b...

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Detalles Bibliográficos
Autores principales: Timofeeva, Olga A., Chasovskikh, Sergey, Lonskaya, Irina, Tarasova, Nadya I., Khavrutskii, Lyuba, Tarasov, Sergey G., Zhang, Xueping, Korostyshevskiy, Valeriy R., Cheema, Amrita, Zhang, Lihua, Dakshanamurthy, Sivanesan, Brown, Milton L., Dritschilo, Anatoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340179/
https://www.ncbi.nlm.nih.gov/pubmed/22378781
http://dx.doi.org/10.1074/jbc.M111.323899