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Efficient Differentiation of Embryonic Stem Cells into Mesodermal Precursors by BMP, Retinoic Acid and Notch Signalling

The ability to direct differentiation of mouse embryonic stem (ES) cells into specific lineages not only provides new insights into the pathways that regulate lineage selection but also has translational applications, for example in drug discovery. We set out to develop a method of differentiating E...

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Detalles Bibliográficos
Autores principales: Torres, Josema, Prieto, Javier, Durupt, Fabrice C., Broad, Simon, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340340/
https://www.ncbi.nlm.nih.gov/pubmed/22558462
http://dx.doi.org/10.1371/journal.pone.0036405