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The Contrasting Effect of Macromolecular Crowding on Amyloid Fibril Formation
BACKGROUND: Amyloid fibrils associated with neurodegenerative diseases can be considered biologically relevant failures of cellular quality control mechanisms. It is known that in vivo human Tau protein, human prion protein, and human copper, zinc superoxide dismutase (SOD1) have the tendency to for...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340346/ https://www.ncbi.nlm.nih.gov/pubmed/22558423 http://dx.doi.org/10.1371/journal.pone.0036288 |