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The Contrasting Effect of Macromolecular Crowding on Amyloid Fibril Formation

BACKGROUND: Amyloid fibrils associated with neurodegenerative diseases can be considered biologically relevant failures of cellular quality control mechanisms. It is known that in vivo human Tau protein, human prion protein, and human copper, zinc superoxide dismutase (SOD1) have the tendency to for...

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Detalles Bibliográficos
Autores principales: Ma, Qian, Fan, Jun-Bao, Zhou, Zheng, Zhou, Bing-Rui, Meng, Sheng-Rong, Hu, Ji-Ying, Chen, Jie, Liang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340346/
https://www.ncbi.nlm.nih.gov/pubmed/22558423
http://dx.doi.org/10.1371/journal.pone.0036288