Implications of Altered Glutathione Metabolism in Aspirin-Induced Oxidative Stress and Mitochondrial Dysfunction in HepG2 Cells

We have previously reported that acetylsalicylic acid (aspirin, ASA) induces cell cycle arrest, oxidative stress and mitochondrial dysfunction in HepG2 cells. In the present study, we have further elucidated that altered glutathione (GSH)-redox metabolism in HepG2 cells play a critical role in ASA-i...

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Detalles Bibliográficos
Autores principales: Raza, Haider, John, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340360/
https://www.ncbi.nlm.nih.gov/pubmed/22558435
http://dx.doi.org/10.1371/journal.pone.0036325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340360/
https://www.ncbi.nlm.nih.gov/pubmed/22558435
http://dx.doi.org/10.1371/journal.pone.0036325

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