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RAB-7 Antagonizes LET-23 EGFR Signaling during Vulva Development in Caenorhabditis elegans
The Rab7 GTPase regulates late endosome trafficking of the Epidermal Growth Factor Receptor (EGFR) to the lysosome for degradation. However, less is known about how Rab7 activity, functioning late in the endocytic pathway, affects EGFR signaling. Here we used Caenorhabditis elegans vulva cell fate i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340361/ https://www.ncbi.nlm.nih.gov/pubmed/22558469 http://dx.doi.org/10.1371/journal.pone.0036489 |