MDM2 Promoter SNP344T>A (rs1196333) Status Does Not Affect Cancer Risk

The MDM2 proto-oncogene plays a key role in central cellular processes like growth control and apoptosis, and the gene locus is frequently amplified in sarcomas. Two polymorphisms located in the MDM2 promoter P2 have been shown to affect cancer risk. One of these polymorphisms (SNP309T>G; rs22797...

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Detalles Bibliográficos
Autores principales: Knappskog, Stian, Gansmo, Liv B., Romundstad, Pål, Bjørnslett, Merete, Trovik, Jone, Sommerfelt-Pettersen, Jan, Løkkevik, Erik, Tollenaar, Rob A. E. M., Seynaeve, Caroline, Devilee, Peter, Salvesen, Helga B., Dørum, Anne, Hveem, Kristian, Vatten, Lars, Lønning, Per E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340411/
https://www.ncbi.nlm.nih.gov/pubmed/22558411
http://dx.doi.org/10.1371/journal.pone.0036263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340411/
https://www.ncbi.nlm.nih.gov/pubmed/22558411
http://dx.doi.org/10.1371/journal.pone.0036263

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