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A powerful test for multiple rare variants association studies that incorporates sequencing qualities
Next-generation sequencing data will soon become routinely available for association studies between complex traits and rare variants. Sequencing data, however, are characterized by the presence of sequencing errors at each individual genotype. This makes it especially challenging to perform associa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340416/ https://www.ncbi.nlm.nih.gov/pubmed/22262732 http://dx.doi.org/10.1093/nar/gks024 |